TY - JOUR
AR - CRSS-2020-2-104
TI - Unusual Case of Pseudomyxoma Peritonei of a Mature Teratoma in Adult Men
AU - Cecilia , Ceribelli
AU - M. Gomes , David
AU - A. , Ayav
AU - J. , Raft
AU - A. , Leroux
AU - F. , Marchal
JO - Case Reports and Series in Surgery
PY - 2020
DA - Mon 05, Oct 2020
SN - 2733-2241
DO - http://dx.doi.org/10.31487/j.CRSS.2020.02.04
UR - https://www.sciencerepository.org/unusual-case-of-pseudomyxoma-peritonei-of-a-mature-teratoma-in-adult_CRSS-2020-2-104 
KW -  Teratoma, pseudomyxoma, HIPEC
AB - Pseudomyxoma peritonei (PMP) is a rare disease usually originating from appendiceal neoplasm and its
incidence is 1-2 cases per million. Extra-appendicular origin is less common and is related to ovary, urachus,
stomach, colon and pancreas cancer. A few cases of mature ovarian teratoma associated with PMP have
been described. We report an extremely rare case of a man treated for a mature teratoma recurrence as a
PMP. A 57-year-old man with multiple surgeries for mature teratoma excision as a newborn was addressed
to our institution. At the age of 55, a surgical exploration found a low-grade PMP. The patient was
asymptomatic, and surveillance was performed. Nine months later, a sub-complete cytoreductive surgery
(CRS) with Mitomycin C HIPEC (hyperthermic intraperitoneal chemotherapy) was performed. One year
later, the residual mass volume was treated by a new CRS with Mitomycin C HIPEC. After a two-year
follow-up patient has no recurrence. PMP extra-appendiceal origin in less than 10%. This is the first reported
case of PMP originating as a mature teratoma recurrence in a man. A few cases describe PMP from ovarian
teratoma in women. Despite PMP’s different origins, gold standard treatment still remains CRS and HIPEC.