TY - JOUR AR - HCS-2020-1-103 TI - Cardiac Microvascular Disease - A Complex Diagnosis? AU - Pieter A., Doevendans AU - Yolande , Appelman JO - Heart and Circulatory System PY - 2020 DA - Mon 27, Apr 2020 SN - DO - http://dx.doi.org/10.31487/j.HCS.2020.01.03 UR - https://www.sciencerepository.org/cardiac-microvascular-disease_HCS-2020-1-103 KW - Microvascular disease, coronary spasm, coronary artery disease AB - Diagnosing microvascular disease in a continuously moving organ like the contracting heart is difficult. Although we have a wide ranch of (non)invasive diagnostic tools available it is still a challenge to reach a solid conclusion. In many patients there is also a combination of risk factors inducing several disease causing mechanisms further obscuring classification strategies. More research will be crucial going form histology to function to determine the position of microvascular disease in patients with unexplained chest pain.