TY - JOUR
AR - JBEM-2019-1-101
TI - Neurologic Wilson Disease Presenting with Acute Delirium And Automatic Writing Behaviour: A Case Report
AU - Deniz , Ertem
AU - Dilşat , Türkdoğan
AU - Engin , Tutar
AU - Esra, Polat
AU - Gazanfer , Ekinci
AU - Gülten , Thomas
JO - Journal of Biology Engineering and Medicine
PY - 2019
DA - Sat 17, Aug 2019
SN - 
DO - http://dx.doi.org/10.31487/j.JBEM.2019.01.01
UR - https://www.sciencerepository.org/neurologic-wilson-disease-presenting-with-acute-delirium-and-automatic-writing-behaviour-a-case-report_JBEM-2019-1-101 
KW - Wilson's disease, delirium, automatic writing behavior
AB - Introduction: Wilson’s disease (WD) is a rare autosomal recessive disorder which leads to abnormal copper
deposition in multiple tissues. Due to extensive deposition of copper in the liver and brain, WD primarily
manifests with a wide range of symptoms as well as psychiatric symptoms.
Method: We report a 15-year-old boy presenting with automatic writing behavior and acute
neuropsychiatric symptoms; splenomegaly and elevated transaminase levels.
Result: A diagnosis of WD was later made, following liver biopsy. Previously, increased writing activity
has been reported in cerebrovascular disease, frontal lobe dementia, temporal lobe epilepsy, Parkinson
disease and multiple sclerosis but not in WD.
Conclusion: This is the first report of increased writing behavior in WD.