TY - JOUR
AR - JSO-2019-1-107
TI - Incidental thyroid cancer in patients undergoing surgery for benign multinodular goitre: A retrospective clinical study
AU - Adnan , ?zpek
AU - Cumhur Selçuk , Topal
JO - Journal of Surgical Oncology
PY - 2019
DA - Fri 29, Mar 2019
SN - 2674-3000
DO - http://dx.doi.org/10.31487/j.JSO.2019.01.007
UR - https://www.sciencerepository.org/incidental-thyroid-cancer-in-patients-undergoing-surgery-for-benign-multinodular-goitre-a-retrospective-clinical-study_JSO-2019-1-107 
KW - Fine needle aspiration biopsy, thyroid carcinoma, thyroidectomy, thyroid nodule goiter
AB - Background and Objectives: In this study, we aimed to analyze the incidence and findings of incidental
thyroid carcinoma (ITC) in patients undergoing thyroidectomy for benign multinodular goitre (MNG).
Methods: A total of 361 consecutive MNG patients with benign (Bethesda II) Fine Needle Aspiration
Cytology (FNAC) results who underwent thyroidectomy without any suspicion of malignancy or
malignancy between January 2009 and January 2018 were retrospectively analyzed. Patients with ITC were
evaluated in terms of age, sex, operation indication, surgery, tumor type, tumor diameter, tumor
multicentricity and complications.
Results: Of the total 361 patients, 288 (79.8%) were female and 73 (20.2%) were male and the mean age
was 48.5 years. One-hundred-and-fourteen (31.6%) of the cases were operated for toxic MNG, 32 (8.9%)
for toxic adenoma, 209 (57.9%) for 4 cm and larger nodule, and 6 (1.6%) for nodules accompanying
parathyroid adenoma. ITC was detected in 42 (11.6%) cases; Papillary thyroid microcarcinoma was found
in 38 (10.5%) and papillary thyroid carcinoma in 4 (1.1%). ITC was found in equal proportion (11.6%) in
patients with and without hyperthyroidism.
Conclusions: We believe that TT or HT is a suitable surgical treatment method in order to reduce the risk
of reoperation and related morbidity in benign MNG patients.