TY - JOUR
AR - JSO-2020-5-103
TI - Microbiome in GIT Cancers: New Frontiers in Personalized Medicine – A Review of Literature
AU - Maha, Saad
AU - Mansour Mohamed, Kabash
AU - Aymn El Sayed, Shafei
AU - Rawan, Ellackany
AU - Ahmed, Atef
AU - Mostafa, Wael
AU - Marwa, Matboli
JO - Journal of Surgical Oncology
PY - 2020
DA - Wed 16, Dec 2020
SN - 2674-3000
DO - http://dx.doi.org/10.31487/j.JSO.2020.05.03
UR - https://www.sciencerepository.org/microbiome-in-git-cancers-new-frontiers-in-personalized-medicine_JSO-2020-5-103 
KW - Gut microbiome, gastrointestinal tract, cancer, therapy, molecular pathogenesis
AB - Every person has a characteristic “enterotype,” the gut components and the environment. Recently, a strong
biological correlation has emerged among the microbiome of the gut, the immune system, cancer
development and pharmacological effects of chemotherapy. In this review, we outline the role of gut
microbiota in the gastrointestinal tract (GIT) cancers pathogenesis and their implications for enhancing the
efficacy of GIT cancer management in clinical practice. We also summarize the molecular pathways linking
gut microbiota and GIT cancers and the effectiveness of manipulating microbiota in GIT cancer therapies
such as personalized cancer therapy.