TY - JOUR
AR - NNB-2020-2-111
TI - Epidemiologic Study of Central Nervous System Tumors in Rwanda
AU - Agabe Emmy , Nkusi
AU - David, Hakizimana
AU - Eric , Shingiro
AU - Paulin , Munyemana
AU - Severien , Muneza
AU - Steven , Nshuti
JO - Neurology and Neurobiology
PY - 2020
DA - Fri 22, May 2020
SN - 2613-7828
DO - http://dx.doi.org/10.31487/j.NNB.2020.02.11
UR - https://www.sciencerepository.org/epidemiologic-study-of-central-nervous-system-tumors-in-rwanda_NNB-2020-2-111 
KW - CNS tumors, epidemiology, incidence, brain tumors, spine tumors, Rwanda, Africa
AB - Introduction: Tumors of the central nervous system (CNS) are primary or secondary neoplasms located
within the craniovertebral cavity. The incidence of CNS tumors is not uniform with variation between
different countries, age groups and races.
Objective: Our study aim was to generate new knowledge of the epidemiology of central nervous system
tumors in Rwanda.
Method: This was an observational retrospective study of all patients diagnosed with CNS tumors in
Rwanda over a period of 10 years, from 1st January 2006 to 31st December 2015.
Results: 466 patients enrolled, (52.2% females, 47.8% males). The median age at diagnosis of was 37 years.
Brain tumors were 82.7%; spine tumor patients were 16.4%. The average annual age-standardized incidence
of CNS tumors was 0.43/100, 0000 person-years and varied with age groups. Tumors of meningothelial
cells represented the majority of brain tumors (31.8%). Metastatic tumors were the far most common spine
tumors category. 55.8 % of CNS tumors reported in our study were histologically confirmed and of nonmalignant meningiomas were the commonest (33.9%).
Conclusion: This is the very first study done on epidemiology of CNS tumors in Rwanda, and generated
data about incidence of CNS tumors in Rwanda and their location and histological distribution.