TY - JOUR AR - RDI-2019-3-104 TI - Sono and photo stimulated Chlorine E6 nanocomposite in tumor-bearing mice: upcoming cancer treatment AU - Ammar Yahya, Kadhim Almamoori AU - Gihan Hosny , Abd Elsamie AU - Metwally Aly, Metwally AU - Samir , Ali JO - Radiology and Medical Diagnostic Imaging PY - 2019 DA - Wed 17, Jul 2019 SN - 2613-7836 DO - http://dx.doi.org/10.31487/j.RDI.2019.03.04 UR - https://www.sciencerepository.org/sono-and-photo-stimulated-chlorine-e6-nanocomposite-in-tumor-bearing-mice-upcoming-cancer-treatment_RDI-2019-3-104 KW - Nano-Chlorine E6, ehrlich tumor, sonodynamic therapy, photodynamic therapy AB - This study was directed at study the effectiveness of cancer targeted therapy using the activated Chlorine E6 nanocomposite (Nano-CE6). Study was applied on male Swiss albino mice, implanted with Ehrlich tumor (EAC) divided into six groups. Two energy sources were used; laser and Ultrasound. Results showed that Nano-CE6 is a potential sensitizer for photodynamic or sonodynamic treatment of tumor. NanoCE6 plays an important role in tumor growth inhibition and cell death induction. Activated Nano-CE6 with both infrared laser and ultrasound has a potential antitumor effect. The results indicated that (FA–NGO– CE6) could be used as a unique nanocomposite for cancer targeted therapy SPDT.