TY - JOUR
AR - SCR-2021-1-119
TI - Complications and Cure Rates of Parathyroidectomy for Primary Hyperparathyroidism with Negative Localization Studies
AU - Bassam , Abboud
AU - Georges, Assaf
AU - Fares, Yared
AU - Alaa, El-Kheir
JO - Surgical Case Reports
PY - 2021
DA - Sat 30, Jan 2021
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2021.01.19
UR - https://www.sciencerepository.org/complications-and-cure-rates-of-parathyroidectomy-for-primary-hyperparathyroidism_SCR-2021-1-119 
KW - Primary hyperparathyroidism, MIBI scan, ultrasound, adenoma, multiple lesions
AB - Purpose: This paper evaluates the outcomes of parathyroidectomy for primary hyperparathyroidism with
negative localization studies.
Methods: All patients with primary hyperparathyroidism with negative preoperative ultrasound and MIBI
scan who underwent parathyroidectomy were retrospectively included. Three groups were defined. Group
1 included the patients with negative ultrasound and MIBI. Group 2 included the patients with negative
ultrasound and positive MIBI. Group 3 included the patients with positive ultrasound and negative MIBI.
Results: In Group 1, 51% and 86% of patients had one adenoma and atypical localizations respectively.
Unique adenoma and atypical localizations were showed in 87% and 93% of patients in Group 2
respectively. In Group 3, 83% and 17% of patients had one adenoma and atypical localizations respectively.
No cervical hematoma was noted. Transient recurrent laryngeal nerve palsy occurred in 2 patients. Seven
patients required postoperative calcium supplementation for 2 to 5 months, and one had recurrent
hypercalcemia at follow-up. Cure rate was 98,3%.
Conclusion: When US and MIBI were negative, multiple lesions and atypical localizations were frequent.
The success rate and postoperative complications were not affected with this event.