TY - JOUR
AR - SCR-2021-5-104
TI - Clinicopathologic Characteristics and Treatment Outcomes of Rectal Gastrointestinal Stromal Tumors: A Retrospective Study
AU - Yi , Lu
AU - Junrong , Chen
AU - Honglei , Chen
AU - Jiachen , Sun
AU - Xianhe , Kong
AU - Weijie , Zhong
AU - Chujun, Li
JO - Surgical Case Reports
PY - 2021
DA - Mon 31, May 2021
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2021.05.04
UR - https://www.sciencerepository.org/clinicopathologic-characteristics-and-treatment-outcomes-of-rectal_SCR-2021-5-104 
KW - GIST, rectal, surgery, recurrence
AB - Background and Study Aims: To investigate the clinicopathologic characteristics, surgical and imatinib management and long-term follow-up outcomes of the rectal gastrointestinal stromal tumors (GISTs).
Patients and Methods: Consecutive patients with rectal GISTs admitted to our center (from January 2013 to June 2018) were chosen. Their history information was viewed, and the follow-up results were obtained by phone or medical records.
Results: Forty-nine patients (32 males and 17 females) were identified, with a median age of 59 years, and 36 patients received surgery. Most (46 patients, 93.9%) of the tumor were located within 6 cm from the anal verge, 18 patients (36.7%) had very low or low risk, and 31 patients (63.3%) had intermediate or high risk. Four kinds of surgery approach were applied in our center: trans-abdominal (8 patients, 22.2%), trans-anal/trans-perineal (15 patients, 41.7%), trans-sacral (12 patients, 33.3%) and abdominoperineal (1 patient, 2.8%). The complication is low and the mortality related to surgery is 0%. After a median follow-up of 705 days (ranged from 48 days to 1677 days), 3 patients (8.33%) were found to have a recurrence.
Conclusion: Trans-anal/trans-perineal and trans-sacral surgery were more commonly used in our study, and for now, the recurrence rate had no difference, but a longer time for follow-up is needed.