Adham Alkadri,Souad Ghattas,Kamal Abi Mousleh,Ribal Abi Hadeer,Youssef Mahfouz,Georges Sakhat,Marwan Haddad,Raja Wakim, Recurrent Cholangiocarcinoma: Case Report and Literature Review American Journal of Surgical Case Reports 2022 2674-5046 http://dx.doi.org/10.31487/j.AJSCR.2022.03.02 https://www.sciencerepository.org/recurrent-cholangiocarcinoma_AJSCR-2022-3-102 Abstract: Conventionally, patients with recurrent cholangiocarcinoma have been treated palliatively, most often with supportive care only. Since intrahepatic cholangiocarcinoma (I-CCA) is an uncommon malignancy, treatment guidelines for I-CCA therapy have a low level of support, and guidelines for the treatment of recurrence are particularly challenging to establish. While a surgical approach is not clearly recommended for recurrent I-CCA in current guidelines, this approach has been reported as reasonable in a particular patient demographic and should be considered [1-3]. Herein we present to you a case of a 56-year-old female patient who presented with local recurrence 1.5 years post resection and was treated surgically.Keywords: Cholangiocarcinoma, recurrent cholangiocarcinoma, CA 19-9, CEA, papillary intraductal cholangiocarcinoma