Amos M Yinnon,Ramzi Kurd,Reuven Friedmann,Yael M. Szterenlicht, A Febrile Return from Mecca: is it the obvious? Clinical Microbiology and Research 2018 2674-418X http://dx.doi.org/10.31487/j.CMR.2018.01.002 https://www.sciencerepository.org/a-febrile-return-from-mecca-is-it-the-obvious_CMR-1-102 Abstract: We describe a 53-year-old female patient with diabetes mellitus and mild hypertension who made the ritual Hajj pilgrimage to Mecca. On the return trip to Jerusalem, she developed a respiratory illness, high fever and chills. We describe the initial and subsequent management of this patient, epidemiological aspects and the surprising final diagnosis. The take-home messages are: first, emergency department staff should demonstrate a high index of suspicion and put patients in isolation who meet specific case definition criteria. Second, even if a certain disease, in this instance MERS-CoV is the obvious diagnosis, open-mindedness and a differential diagnosis are always necessary in order to avoid misdiagnosis. Keywords: Middle East respiratory Syndreom (MERS), MERS-CoV (Coronavirus), Adult Respiratory Syndrome (ARDS) ,Isolation procedures.