Dawood Findakly,Mohammed Al-Charakh ,Surabhi Amar ,
A Unique Case of Chronic Myeloid Leukemia Occurring in an Adolescent Male
Clinical Oncology and Research
2020
2613-4942
http://dx.doi.org/10.31487/j.COR.2020.03.13
https://www.sciencerepository.org/a-unique-case-of-chronic-myeloid_COR-2020-3-113 
Abstract: Background: Patients with chronic myeloid leukemia (CML) usually present in elderly age and rarely in
the adolescents and young adults (AYA) population. There is a limited understanding of disease
management and survival outcomes in this group of patients.
Case Presentation: An 18-year-old man presents to our hospital for abdominal pain and weight loss.
Examination pertinent for splenomegaly and labs significant for profoundly elevated white cells count. FISH
was positive for BCR/ABL1 fusion gene, and thus, he was diagnosed with CML and treated with TKI with
clinical improvement.
Conclusion: Tailoring CML novel therapeutic strategies in the AYA population to different disease
characteristics will better advance our understanding of this disease in this patient population.Keywords: Chronic myeloid leukemia, adolescents and young adultstyrosine, kinase inhibitor