Shashanka  K Prasad,D. Devananda,
Evaluating the Anticancer Potentials of Methanol Extracted Annona muricata Fruit Pulp and Seed(s) Phytochemicals
Clinical Oncology and Research
2020
2613-4942
http://dx.doi.org/10.31487/j.COR.2020.08.04
https://www.sciencerepository.org/evaluating-the-anticancer-potentials-of-methanol-extracted-annona-muricata_COR-2020-8-104 
Abstract: Annona muricata L. has been widely used in traditional medicine for the treatment of various diseases
ranging from fever to cancer. In this study, we evaluate the in vitro anticancer potential of methanol
extracted A. muricata fruit pulp (AMPM) and seeds (AMSM) phytochemicals against breast (MCF-7),
cervical (HeLa), prostate (PC-3) and colorectal (HCT-116) cancer cell lines. Additionally, the in vitro antiinflammatory and antioxidant activities of the extracts have been carried. The findings suggest that the
AMSM is the most potent among the either extracts. Notwithstanding, both AMPM and AMSM showed
significant dose and cell line-dependent anticancer potential(s).
Keywords: Annona muricate, anticancer, antioxidant, anti-inflammatory, anti-proliferative, cancer phytotherapy