Khaled Saleh  Ben Salah,Fatma  M. Emaetig,Ebrahim H.  El Mahjoubi,Abdalla  O. Jebriel,Nada  A. Oshah,Firas  K. Abdulmalik,Mohamed  A. Elfagieh,Wafa  A. Baba,Mohamed  O. Altaweel,Naji  Zoubia,Alla  Shoaoba,Monir  Abdelmollah,Yaser  O. Howayw,Abdouldaim  Ukwas,Abdulhakim W Zaggut,
Dyskeratosis Congenita: Squamous Cell Carcinoma of the Buccal Mucosa on a Background of Lichen Planus – A Case Report During COVID-19 Pandemic
Clinical Oncology and Research
2021
2613-4942
http://dx.doi.org/10.31487/j.COR.2021.05.02
https://www.sciencerepository.org/dyskeratosis-congenita-squamous-cell-carcinoma-of-the-buccal_COR-2021-5-102 
Abstract: Dyskeratosis Congenita is a severe disorder that involves several systems in the human body and is well-known for its transmission hereditarily through generations. The triad of a) reticular atrophy of the skin with pigmentation b) dystrophy of the nails c) leukoplakia of the oral mucosa characterises this uncommon disorder, which most commonly affects men. One of the key reasons for premature death in this disease is malignant transformation within areas of mucosal hyperkeratosis. In Dyskeratosis Congenita, the simultaneous existence of squamous cell carcinoma (SCC) with lichen planus and or lichenoid reactions in the mucosa of the oral cavity is a rare, stated condition. This report discusses a case of a Libyan male patient affected by Dyskeratosis Congenita that ended with buccal mucosal squamous cell carcinoma developed on a lichen planus background after thirty years of suffering at the age of 64.Keywords: Carcinoma, congenita, dyskeratosis, oral, mucosa, squamous