Edoardo Sicurezza,G. Palazzo ,T. Mattina ,V. Nicotra , Oral Manifestation in a Patient with Bilateral Duane Syndrome: A Case Report Case Reports in Dental and Oral Biology 2019 http://dx.doi.org/10.31487/j.CRDOB.2019.01.02 https://www.sciencerepository.org/oral-manifestation-in-a-patient-with-bilateral-duane-syndrome_CRDOB-2019-1-102 Abstract: Duane syndrome is a rare retraction anomaly characterized by congenital non-progressive horizontal ophthalmoplegia and other systemic signs. No data has been yet registered about oral manifestation of Duane syndrome. In this article we present a six years old male patient was diagnosed as having Duane retraction syndrome. He presented skeletal Class III with both maxillary and mandibular protrusion, counter clock-wise mandibular rotation, lingualized maxillary and mandibular incisors, first mandibular molar agenesis, asymmetric morphology of the mandibular condyles and multiple decay lesions. Posteroanterior x-ray showed an asymmetrical craniofacial structure. The aim of this case report was to describe the oral signs of a patient affected by DRS.Keywords: Duane syndrome, oculomotor anomaly, dental agenesis, asymmetrical craniofacial structure