Lai Lai Soe,Yi Yi  Htun,Yee Yee  Tin,
Antibacterial Drugs Utilization among Patients Admitted to Medical Wards of Magway Regional Hospital
Drug and Drug Abuse
2019
2674-5062
http://dx.doi.org/10.31487/j.DDA.2019.01.05
https://www.sciencerepository.org/antibacterial-drugs-utilization-among-patients-admitted-to-medical-wards_DDA-2019-1-105 
Abstract: Background: Drug utilization studies are important elucidation tools for prescribing habits in particular
therapeutic field and they play a key role in helping the healthcare personnel to understand, interpret and
improve the prescribing, administration and use of medications.
Objectives: This study was undertaken to identify amount of antibacterial drugs used and utilization
patterns of antibacterial drugs in medical wards of Magway Regional Hospital.
Methods: This study is a hospital-based, cross-sectional, descriptive study and was carried out for a period
of four months. Data regarding antibacterial prescription during hospital stay were collected from medical
record files of patients. The data were evaluated by Microsoft Excel software.
Results: In this study, the most common indications for antibacterials were respiratory tract infections
(43.34%) followed by gastrointestinal tract infections (16.27%). Out of 879 patients, 52.10% were
prescribed by single antibacterial agent and in 47.90%, combination of antibacterials was necessary to be
given. Antibacterials were prescribed by oral route in 29.58% and parenteral route were prescribed in
29.35% while 41.07% patients received antibacterials by both oral and parenteral routes. Antibacterials were
prescribed with generic name in 64% and trade name in 36%. Cephalosporins were the most commonly
prescribed drugs, 68.26%, followed by penicillin groups and quinolones, 53.58% and 16.27% respectively.
In this study, 13 drugs included in DU90% segment were amoxicillin and β-lactamase inhibitor combination
(22.26%), ceftriaxone (16.05%), cefuroxime (8.26%), levofloxacin (7.67%), amoxicillin and flucloxacillin
combination (7.27%), metronidazole (6.89%),clarithromycin (4.74%), cefixime (4.68%), co-trimoxazole
(4.24%), ceftazidime (2.6%), azithromycin (2.46%), cefoperazone and β-lactamase inhibitor combination
(1.65%) and clindamycin (1.64%).
Conclusions: The findings from this study will provide the documentary evidence regarding antibacterial
utilization patterns in treatment of a variety of infections and antibacterial drugs include in DU90% segment.
This information generally contributes data for making decision of purchasing medicines or preparing drug
budgets.Keywords:  Drug utilization, antibacterial drugs, magway regional hospital