Ganesh Sai Sandeep Kumar,L. Krishna Prasad,P. Srinivas Chakravarthi,P. Raja Satish,Anand Vijay S,Vidya Sagar B,K. S. Deekshith, Evaluation of Socket Preservation Using Collagen Plug and Injectable Platelet Rich Fibrin in Extracted Sockets of Mandibular Molars: A Split Mouth Study Dental Oral Biology and Craniofacial Research 2023 2613-4950 http://dx.doi.org/10.31487/j.DOBCR.2023.02.01 https://www.sciencerepository.org/evaluation-of-socket-preservation-using_DOBCR-2023-2-101 Abstract: Aim and Objectives: Evaluation of socket preservation using collagen plug and injectable platelet rich fibrin in extracted sockets of mandibular molars. To evaluate wound healing and bone density using collagen plug and I-PRF and to compare wound healing and bone density between collagen plug and I-PRF. Methodology: This experimental study involves 13 healthy patients at the Sibar Institute of Dental Sciences and Hospital in Guntur, Andhra Pradesh, India, who underwent mandibular molar extraction under local anesthesia. Patients underwent clinical and radio-graphic examinations and received periodontal treatment. The study involved extraction of right and left mandibular molar teeth, AbGel placement, collagen plug placement, and sockets secured with sutures and pressure packs. Postoperative pain, swelling, and wound healing were assessed using Wong-Baker faces pain rating scale, VAS scale, and LANDRY healing index. CBCT was obtained after 1 month and 3 months after extraction for bone quality assessment. Results: In the study, there were 69.2% men and 30.8% women. According to the study, 14.3% of individuals in the collagen plug group and 85.7% of those who received injectable platelet-rich fibrin experienced very good wound healing. On the first and seventh days, the mean pain intensity was lower in the injectable group, but there was not a noticeable distinction between the groups. The injectable group had the lowest swelling score, but by day seven, it had dramatically decreased. At the third month, the collagen plug group had the highest bone density readings, with no discernible difference between the groups. Conclusion: It can be concluded that I-PRF can be utilized as an alternative to collagen plug.Keywords: Biocompatible materials, collagen, guided tissue regeneration, socket bone healing