Yasemin Benderli Cihan, Is Microsatellite Instability Important in Response to Radiotherapy in Patients with Rectal Cancer? International Journal of Cancer Science and Therapy 2020 http://dx.doi.org/10.31487/j.IJCST.2020.01.03 https://www.sciencerepository.org/is-microsatellite-instability-important-in-response-to-radiotherapy_IJCST-2020-1-103 Abstract: MSI is the indicator of a DNA repair error that may lead to mutation accumulation formed in the cell. Although there are conflicting studies in the literature, in many studies it has been revealed that MSI has predictive and prognostic effect on response to RT in rectal cancer.Keywords: Microsatellite instability, radiotherapy, rectal cancer