Biswanath Mukhopadhyay ,Debasish Mitra,Bikramjit Das, Meconium Peritonitis: Report of Three Cases and Review of Literature International Journal of Surgical Case Reports 2020 2674-4171 http://dx.doi.org/10.31487/j.IJSCR.2020.03.06 https://www.sciencerepository.org/meconium-peritonitis-report-of-three-cases-and-review-of-literature_IJSCR-2020-3-106 Abstract: Meconium peritonitis carries a high risk of mortality in neonates. The etiology may be varied, and the perforation may occur either antenatally or in the immediate postnatal period. A strong clinical suspicion is required, and urgent management is crucial for survival without loss of functional gut. The underlying cause of intestinal obstruction must be carefully investigated. Postoperative management with parenteral nutrition, management of short gut and assessment of neurodevelopment are crucial for better quality of life. We present here three cases of complicated meconium peritonitis with perforation. We highlight the importance of high clinical suspicion and timely management resulting in good clinical outcomes.Keywords: Meconium, peritonitis, neonates, laparotomy