Deniz  Ertem,Dilşat  Türkdoğan,Engin  Tutar,Esra Polat,Gazanfer  Ekinci,Gülten  Thomas,
Neurologic Wilson Disease Presenting with Acute Delirium And Automatic Writing Behaviour: A Case Report
Journal of Biology Engineering and Medicine
2019

http://dx.doi.org/10.31487/j.JBEM.2019.01.01
https://www.sciencerepository.org/neurologic-wilson-disease-presenting-with-acute-delirium-and-automatic-writing-behaviour-a-case-report_JBEM-2019-1-101 
Abstract: Introduction: Wilson’s disease (WD) is a rare autosomal recessive disorder which leads to abnormal copper
deposition in multiple tissues. Due to extensive deposition of copper in the liver and brain, WD primarily
manifests with a wide range of symptoms as well as psychiatric symptoms.
Method: We report a 15-year-old boy presenting with automatic writing behavior and acute
neuropsychiatric symptoms; splenomegaly and elevated transaminase levels.
Result: A diagnosis of WD was later made, following liver biopsy. Previously, increased writing activity
has been reported in cerebrovascular disease, frontal lobe dementia, temporal lobe epilepsy, Parkinson
disease and multiple sclerosis but not in WD.
Conclusion: This is the first report of increased writing behavior in WD.Keywords: Wilson's disease, delirium, automatic writing behavior