Domenico Facchin,Tioni C,Daleffe E,Rebellato L,Antonutti M,Sut D,Proclemer A, Subcutaneous Implantable Cardioverter Defibrillator and LifeVest Saving Lives in Challenging Scenarios Journal of Clinical and Medical Case Reports 2020 2733-2268 http://dx.doi.org/10.31487/j.JCMCR.2020.03.03 https://www.sciencerepository.org/subcutaneous-implantable-cardioverter-defibrillator-and-lifevest-saving-lives_JCMCR-2020-3-103 Abstract: Introduction: According to guidelines, ICD should be implanted in selected patients for primary or secondary prevention. The increasing number of procedures leads to a growth of infective complications. Case Summary: We report two cases of ICD implantation complicated with severe infections. The first procedure was complicated by endocarditis and septic shock, the second one by septic shock. After antibiotics and ICD explantation, a wearable cardioverter defibrillator (WCD) was used as a bridge to subcutaneous ICD (S-ICD). Conclusion: These two cases demonstrate the benefits of the S-ICD, but also the chance to treat high-risk patients with WCD as bridge-to-procedure, allowing full recovery before a new implantation.Keywords: Subcutaneous ICD, infective complications, septic shock, wearable cardioverter defibrillator, case report