Qianyi  Zhou,Jianming  Ma,Zejia  Zhang,Ziqian  Wang,
Effect Evaluation of Transfat Decoction on Obesity Mice Induced by High-Fat Diet
Journal of Food Nutrition and Metabolism
2019
2674-2411
http://dx.doi.org/10.31487/j.JFNM.2019.01.01
https://www.sciencerepository.org/effect-evaluation-of-transfat-decoction-on-obesity-mice-induced-by-high-fat-diet_JFNM-2019-1-101 
Abstract: Objective: To investigate the effect of Tranfat Decoction on obesity mice induced by high-fat diet.
Methods: 90 healthy SPF C57BL/6 male mice aged 3 weeks were selected and 15 of them were treated as
normal group. The remaining 75 mice were used as model group to induce obesity. After successful
modeling, drug intervention was given for 6 weeks, and body weight, body fat content and blood fat level
of the mice were measured.
Results: After 6 weeks of drug intervention, compared with the model blank group, the body weight of the
drug administration group all decreased to different degrees (P < 0.05). TC, TG, LDL-C and HDL-C levels
were significantly different in the high-dose group (P < 0.05). Fat volume was lower in the administration
group (P < 0.05).
Conclusion: Tranfat Decoction can reduce body weight, body fat content and blood fat level in obese mice
induced by high-fat diet.Keywords: Tranfat, Decoction obesity, high-fat diet, mice