Alessandro Crisci,Michela  Crisci,Raffaele  D’Adamo,
Leiomiosarcoma of the Subcutaneous Tissue the Difficulties of Clinical Diagnosis: Description of a Case
Surgery Case Reports
2020
2733-225X
http://dx.doi.org/10.31487/j.JSCR.2020.02.06
https://www.sciencerepository.org/leiomiosarcoma-of-the-subcutaneous_JSCR-2020-2-106 
Abstract: Aims: Leiomyosarcomas are infrequent malignant tumors of smooth muscle, mainly derived from blood
vessels or viscera. Superficial leiomyosarcomas are rare soft tissue sarcomas resulting from the dermis or
subcutaneous tissue. They show a preference for proximal ends and tend to be slow-growing. They clearly
show different histological and prognostic characteristics depending on whether they are cutaneous or
subcutaneous.
Case Report: We reported the case of subcutaneous leiomyosarcoma resulting in the medial subinguinal
region of the right thigh in a 58-year-old female. Leiomyosarcoma is an entity whose clinical presentation
may appear non-specific, making diagnosis difficult. We discussed the case with a brief review of the
literature and the difficulties of a first approach clinical diagnosis.
Conclusion: In conclusion, a long period of patient follow-up is recommended to capture a subsequent
malignant progression of the disease.Keywords: Immunohistochemistry, subcutaneous leiomyosarcoma, smooth muscle differentiation, soft tissue tumors