Yoichiro Shibuya,Akio Nishijima ,Junya Oshima,Kaoru  Sasaki,Masahiro Sasaki,Mitsuru Sekido,Yukiko Aihara,
Disappearance of Internal Jugular Vein Thrombosis After Use of Edoxaban Following Head and Neck Reconstruction: A Case Report
Journal of Surgical Oncology
2020
2674-3000
http://dx.doi.org/10.31487/j.JSO.2020.01.08
https://www.sciencerepository.org/disappearance-of-internal-jugular-vein-thrombosis_JSO-2020-1-108 
Abstract: Internal jugular vein thrombosis (IJVT) is a complication of neck dissection. After head and neck
reconstruction, flap congestion due to IJVT may lead to flap necrosis, and early diagnosis and treatment
should be considered. We experienced a case of disappearance of IJVT in which edoxaban was administered
after free-flap reconstruction, and the entire flap survived. Edoxaban has few bleeding complications and
was useful as a single drug approach for IJVT after head and neck reconstruction.Keywords: Internal jugular vein thrombosis, Head and Neck reconstruction, Edoxaban