Pietro Gareri,Valeria Graziella Laura Manfredi,
Takotsubo Cardiomyopathy: An Unusual Case Report in a Patient Affected with Alzheimer’s Disease
Neurology and Neurobiology
2019
2613-7828
http://dx.doi.org/10.31487/j.NNB.2019.03.02
https://www.sciencerepository.org/takotsubo-cardiomyopathy-an-unusual-case-report-in-a-patient-affected-with-alzheimer-s-disease_NNB-2019-3-102 
Abstract: We describe a case report regarding an elderly woman affected with Alzheimer’s disease (AD), presenting
to the ER for chest pain, and showing ST-segment elevation on electrocardiography, and elevated cardiac
enzyme levels. She was hospitalized and after a number of laboratory and instrumental exams she was
diagnosed Tako-tsubo syndrome. One year after the event she is feeling fine, electrocardiogram is normal,
and no symptoms of cardiac heart failure are present. Tako-tsubo syndrome is a stress-induced
cardiomyopathy that involves left ventricular apical akinesis and mimics acute coronary syndrome. It was
first described in Japan in 1991, it is rare (1:36.000) with 1:3 male/female ratio and survival is usually 96%.
The novelty of this case-report is due to its rarity and to the onset of the disease in an elderly patient affected
with AD.Keywords: Tako-Tsubo syndrome, dementia, heart failure, cardiomyopathy