Michael W. Williams,Justin E. Karr,Alyssa M. Day,Amanda C. Glueck,Siddharth Kapoor,Dong Y Han, Post-Traumatic Headache is Associated with Worse Anxiety and Mood Symptoms in Adolescent Mild Traumatic Brain Injury Neurology and Neurobiology 2022 2613-7828 http://dx.doi.org/10.31487/j.NNB.2022.02.04 https://www.sciencerepository.org/post-traumatic-headache-is_NNB-2022-2-104 Abstract: This study examined the relationships between post-traumatic headache (PTH) and mental health symptoms after concussions to inform adolescent concussion management. Headache is the most common complaint following adolescent concussion. In this sample of 123 adolescents with concussion, there was a 5-fold increase in odds of clinically elevated anxiety, as well as increased mental health symptoms (anxiety, depression, anger, and disruptive behaviours), among adolescents with PTH relative to those without PTH. Adolescents with headache following concussions are vulnerable to worse mental health outcomes, particularly anxiety, and may benefit from routine monitoring of mental health symptoms for early detection and intervention.Keywords: Anxiety, concussion, post-traumatic headache, adolescent, mental health, depression