Decsi Krisztián ,Gyűrűs Péter ,Hamed Arian ,Kránitz Noémi ,Kullmann Tamás,Sipőcz István ,
Granulocytic Sarcoma with Meningeal Leukemia. A Case Report
Radiotherapy and Clinical Oncology
2020
2674-2497
http://dx.doi.org/10.31487/j.RCO.2020.01.02
https://www.sciencerepository.org/granulocytic-sarcoma-with-meningeal-leukemia_RCO-2020-1-102 
Abstract: The case of a 63-year-old woman is presented who developed 18 years after undergoing allogenic bone
marrow transplantation for chronic myeloid leukaemia a granulocytic sarcoma localised in the presacral
region. Complete radiologic remission was obtained with the administration of imatinib. She developed a
metachron granulocytic sarcoma in the right frontal region associated to leptomeningeal infiltration.
Complete clinical and near complete radiological remission was obtained with the administration of nilotinib.
The patient was finally lost of progression of the frontal and meningeal localisations 45 months after the
presentation of the first presacral lesion. Throughout the follow-up no sign of systemic leukaemia was
detected.Keywords: Granulosarcoma, chronic myeloid leukaemia, imatinib, nilotinib