M. Rimbault,L. Paquier,M. Tooulou,N. Abboud,Philippe Simon, Oncoplastic Management of a Giant Buschke Lowenstein Genital Tumor in a Nonimmunocompromised Patient Surgical Case Reports 2020 2613-5965 http://dx.doi.org/10.31487/j.SCR.2020.02.12 https://www.sciencerepository.org/oncoplastic-management-of-a-giant-buschke-lowenstein-genital-tumor-in_SCR-2020-2-112 Abstract: Buschke-Löwenstein tumor (BLT) is a rare but impressive and aggressive entity and is mostly associated with Human Papilloma Virus (HPV) 6 or 11 infection in immunocompromised patients. It stands out because of the importance of the recurrences and the risk of progression to a malignant tumor. The first-line treatment remains local radical surgery. Other treatments are controversial, including radiotherapy, chemotherapy, and immunotherapy. We report a new case regarding the management of a giant BLT in a non-immunocompromised woman, treated in a three-staged approach, starting with a radical excisional surgery, followed by a delayed reconstruction and then radiotherapy.Keywords: Bushke lowenstein, oncoplastic surger, vulvar carcinoma