George  Oosthuizen,
Wilkie’s Syndrome Following Weight Loss in a Trauma Patient
Surgical Case Reports
2020
2613-5965
http://dx.doi.org/10.31487/j.SCR.2020.10.06
https://www.sciencerepository.org/wilkie-s-syndrome-following-weight-loss-in-a-trauma-patient_SCR-2020-10-106 
Abstract: Wilkie’s syndrome, or superior mesenteric artery syndrome, is a rare condition of duodenal obstruction
caused by compression of the superior mesenteric artery on the third part of the duodenum. The diagnosis
should be considered in a patient who has experienced significant weight loss and now presents with
persistent vomiting, especially if the vomiting occurs with the patient in the supine position and is alleviated
by the lateral or prone position. The diagnosis can be confirmed by imaging studies demonstrating
compression of the third part of the duodenum, and the main aim of treatment should be to pass a feeding
tube beyond the point of obstruction to allow enteral feeding. The condition improves spontaneously with
weight gain. Further treatment options include parenteral feeding and operative bypass in select cases. Here
we present a case of Wilkie’s syndrome in a trauma patient with significant weight loss, together with a
review of the literature on this interesting topic.Keywords:  Wilkie’s syndrome, superior mesenteric artery syndrome, cast syndrome, mesenteric root syndrome, chronic duodenal ileus, intermittent arterio-mesenteric occlusion