Daniel Grandmougin,Yihua Liu,Marie-Reine Hirschi,Samia Kara Mostefa,Marie-Alix Régnier,Claire Courrier,Frédéric Quiring,Pan Dan,Juan-Pablo Maureira, Rupture of Sinus of Valsalva Mimicking Aortic Root Dissection: Surgical Management and Factors Influencing Immediate Survival Surgical Case Reports 2021 2613-5965 http://dx.doi.org/10.31487/j.SCR.2021.01.09 https://www.sciencerepository.org/rupture-of-sinus-of-valsalva-mimicking-aortic-root-dissection_SCR-2021-1-109 Abstract: Rupture of giant aneurysm of sinus of Valsalva usually requires surgery to prevent life-threatening complications from occurring. We report the case of a 55-year-old patient with a previous history of aortic valve replacement who was urgently referred to our institution with a superior vena cava syndrome and dyspnea. CT-scan initially misdiagnosed a dissection of the aortic root that was ultimately a contained rupture of a giant aneurysm of the non-coronary sinus of Valsalva. Despite a sudden hemodynamic deterioration with a collapse and cardiac arrest, urgent salvage surgery was successfully performed with an uneventful outcome. Physiopathogeny of hemodynamic profiles influencing immediate survival and surgical technique are discussed in this report. Keywords: Aneurysm, sinus of Valsalva, non-coronary sinus, rupture, lethal tamponade, U-shaped dacron patch