Koichi  Endo,Hideyuki  Arima,Tomohiko  Hasegawa,Yu  Yamato,Go  Yoshida,Tomohiro  Banno,Shin  Oe,Yuki  Mihara,Hiroki  Ushirozako,Tomohiro  Yamada,Yuh  Watanabe,Koichiro  Ide,Keiichi  Nakai,Kenta  Kurosu,Yukihiro  Matsuyama,
Spinal Tumor Resection with Intraoperative Computed Tomography Navigation in Tumor-Induced Osteomalacia: A Case Report
Surgical Case Reports
2021
2613-5965
http://dx.doi.org/10.31487/j.SCR.2021.06.05
https://www.sciencerepository.org/spinal-tumor-resection-with-intraoperative-computed-tomography-navigation_SCR-2021-6-105 
Abstract: This is the first report using intraoperative CT navigation for Tumor-induced Osteomalacia (TIO) lesions of the spine. TIO is a rare paraneoplastic disorder caused by tumors secret Fibroblast growth factor 23 secreted by tumor tissue. Surgical resection of the main tumor is the only definitive treatment. However, the tumor is usually small, and it hard to find it, and it tends to be seen when the recurrence is caused by the difficulty of whole tumor resection. A 57-year-old woman presented with a rare case of TIO located in T10 vertebra body. Using the intraoperative CT navigation, we resected the tumor in the T10 vertebral body very effective for accurate localization of the tumor and helpful for guidance of resection area and confirmation for excision of tumor. As a treatment for TIO, we report a tumor resection with intraoperative computed tomography navigation that made it possible to resect tumor in T10 vertebrae precisely and safely, which is small and difficult and dangerous access.Keywords: Tumor-induced osteomalacia, spinal tumor resection, intraoperative computed tomography navigation, phosphaturic mesenchymal tumor, fibroblast growth factor 23