Chiseng Lei,Jiamei Hu,Yuan Li,Yude Xie,Jie Zhang,Ningxia Wang,Yuhua Ma,Shaohua Qu,
Benign Phyllodes Tumor and Ductal Carcinoma in situ Coexist in the Same Breast Tumor: A Case Report and Review of the Literature
Surgical Case Reports
2022
2613-5965
http://dx.doi.org/10.31487/j.SCR.2022.11.05
https://www.sciencerepository.org/benign-phyllodes-tumor-and_SCR-2022-11-105 
Abstract: Background: Breast phyllodes tumor (PT), the rare fibroepithelial mammary tumor is composed by mesenchymal and epithelial components, only 1%~2% of which were accompanied by epithelial breast cancer. The incidence of non-invasive ductal carcinoma (DCIS) arising in benign PTs is even rarer. There is no certain treatment for it currently because of the low incidence of PT with DCIS. 
Case Description: Here, we report a 57-year-old female patient who was diagnosed with ductal carcinoma in situ arising in a benign phyllodes tumor of the breast. Mastectomy and sentinel lymph nodes biopsy were performed, and endocrine therapy was administrated to the patient. No recurrence was noted during follow-up.
Conclusion: Since PTs are prone to recurrence, adjuvant therapy should be considered comprehensively by the histopathological results after surgical treatment. In addition, regular follow-up is recommended.Keywords: Phyllodes tumor, ductal carcinoma in situ, breast cancer, mastectomy