Prognostic Factors for Cervical Cancer in FIGO-Stages IA-IIB in a 10-Year Period in the Region of Uppsala, Sweden: Population Cohort Study

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them coherent?

A: Very good

Comments:

The study is well designed and executed. The Methods and Results are adequately described. It is well supported with briefly explained figure and tables. The Discussion offers a thorough and detailed analysis of the findings of the present study taking all the relevant literature into account. This study suggested that tumor differentiation grade might be a prognostic factor in women with squamous cervical cancer, particularly in early-stage disease. The Conclusion section aptly summarizes from the results by comparing the three histological types that survival analysis reported worse survival for patients with adeno-squamous cervix cancer.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate for the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legends and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This retrospective study investigates what impact do the three main morphological subtypes (squamous cell carcinoma, adenocarcinoma and adeno-squamous carcinoma) have on recurrence and survival. This study holds significance as it consists of the complete population of cervical cancer cases in FIGO-stages IA-IIB admitted to one single institution for decision of treatment, with detailed data on tumor characteristics, treatment and follow-up. The ungraded tumors in this study were usually of squamous cell carcinoma histology.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team