Dexmedetomidine as an Anaesthetic Adjunct in Patients Undergoing Elective Off-Pump Coronary Artery Bypass Graft Surgery

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The Discussion puts forth the rationale for taking up the study, effectively describes the relevant literature and enlists the implications of the findings from the present study in that context. The Methods and Results are adequately described. The study is well supported with briefly explained tables. The Conclusion is consistent with the evidences presented in this article. It states that dexmedetomidine is a viable option as an anaesthetic adjunct in a loading dose of 1µg/Kg followed by an infusion of 0.6 µg/Kg. The study aptly recommends further research to show if this provides any outcome benefits.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This study aims to study the hemodynamic profile of dexmedetomidine during induction and distal anastomosis of coronary arteries in patients undergoing off-pump coronary artery bypass (OPCAB) in comparison to the institutional practice of using midazolam. The major drawbacks of dexmedetomidine are its propensity to cause bradycardia and hypotension. The hemodynamic parameters during distal anastomosis of individual vessels have been reported in the present study. Dexmedetomidine based anaesthesia has been shown to decrease isoflurane requirements to maintain hemodynamic parameters within predetermined limits and therefore, dexmedetomidine is well appreciated as an anaesthetic adjunct with consistent results that it reduces anaesthetic requirements.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team