Innovative Observation of a 266-nm Laser Inhibiting Egg Laying in Caenorhabditis elegans

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for

researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Very good

Comments:

Using Caenorhabditis elegans as model organism, the study aims to prove that light can not only alter a cell, but also a small organism and influence its life activities. The use of a different laser intensity is unique to this study and can pave the way for further investigations. The Discussion puts forth the rationale for taking up the study, effectively describes the relevant literature and enlists the implications of the findings from the present study in that context. It is well supported with briefly explained figures. The data from this study holds potential in providing great insights for future phototherapy.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the paper's length adequate to the topic's significance? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This study innovatively uses a 266-nm laser to irradiate Caenorhabditis elegans for only one second and observes a significant inhibition of the overall number of eggs laid. The study holds significance as this is the first study to establish how light with a wavelength of 266-nm can influence a life activity such as laying eggs in C. elegans. It is also the first study designed for C. elegans, wherein the impact on the initial and total quantity of eggs laid has been studied. The article provides significant results enlightening a potential that light can also effectively regulate the behaviour of life.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team