Immune Response Role of Angiogenesis Inhibitors

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Excellent

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Insufficient

Comments:

Keywords are missing.

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The study shows that angiogenesis inhibitors enhance immune response toward tumor cells. The study is well supported with figures and tables. The Conclusion section adequately covers the promising results of combined anti-angiogenesis and immunomodulatory treatment, which also highlights the potential for other combinations including chemotherapy that need to be investigated in the field of cancer therapy.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: This article talks about angiogenesis in the tumor microenvironment and signaling pathways involved with emphasis on FDA approved angiogenesis inhibitors. Angiogenesis inhibition has been studied meticulously through the years, leading to the evolution of anti-angiogenesis cancer therapeutics with FDA approval. Although angiogenesis inhibitors have been developed to treat various types of cancers, adverse effects are still present with treatment.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Thanks,
Science Repository Team