Subependymal Giant Cell Astrocytoma without Clinically or Genetically Identifiable Tuberous Sclerosis Complex: A Case Report

Review Data

Purpose and Significance of Study: This is a case report of rare entity of subependymal giant cell astrocytoma (SEGA) in a patient without clinical evidence of tuberous sclerosis or somatic TSC1/2 mutations. There are just two such previously published events. This manuscript will help provide clinicians with insight on low grade periventricular tumors and help augment our collective understanding of such a rare sporadic event.

Fit with Scope of Journal: The manuscript is of very high interest for the journal Case Reports and Series in Surgery.

The Discussion is apt. It puts the exceptional rarity of the present case in context and elaborately explains the rationale behind the pre-, peri- and post-operative course followed with reference to the relevant literature.

o   The manuscript is well-written. A couple of very minor errors (already corrected in the galley proof) are listed below –

 

·       In the last sentence of the 2^nd paragraph of Case Description, “area of residual” must be replaced with “residual area”.

·       In the last sentence of the 1^st paragraph of the Discussion, “sequelae” is misspelled.

Author Info

Karim Hafazalla Donald Y. Ye Timothy Chao Mark Curtis Christopher J. Farrell

Corresponding Author

Christopher J. Farrell
Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

Article Info

Article Type

Case Report

Publication history

Received: Thu 04, Jun 2020
Accepted: Fri 03, Jul 2020
Published: Fri 31, Jul 2020

Copyright

© 2023 Christopher J. Farrell. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.CRSS.2020.02.03