Innovative Approach of Endosonographic Radioactive Labeling of an Ectopic Parathyroid Adenoma by Technetium-99m Human Serum Albumin: A Case Report

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments: The Discussion gives an overview of the cause of primary hyperthyroidism (PHPT). The authors explained the possible symptoms and surgical procedures of PHPT, providing relevant literature. The case is considered the first report of EUS-guided injection of a radioactive tracer (99mTc-HSA). The authors also suggests that the use of the method for preoperative labelling of retroesophageally located tumors may be helpful to the surgeons for precise and less invasive surgical excision.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: The manuscript illustrates an innovative approach to endosonographic radioactive labeling of an electric parathyroid adenoma with the help of Technetium-99m human serum albumin. The case presents a 73-year-old patient who was diagnosed with subclinical primary hyperparathyroidism. The case mainly highlights the surgical procedure of an ectopic retroesophageal adenoma resected under gamma-probe guidance after preoperative radioactive targeting.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team