Renal Pelvis and Renal Calices Sarcomatoid Carcinoma: A Case Report

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Excellent

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The case description is adequate. The Discussion explains the challenges in treating the patient in the present case clearly. It also offers useful suggestions with respect to the treatment regimen. The Conclusion states that renal pelvis and renal calices sarcomatoid carcinoma is a highly malignant tumor and difficult to diagnose at its early stage due to the lack of specific clinical manifestations. There are no standard treatment guidelines for this disease and most reported cases undergo nephroureterectomy. More data are needed in the future to make evidence-based treatment decisions.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: This case report presents the case of a 63-year-old man with recurrent left flank pain for two years. The pathological diagnosis following left nephrectomy indicated renal pelvis and renal calices sarcomatoid carcinoma. Sarcomatoid carcinoma is one of the malignant neoplasms characterized by the ability to differentiate into both epithelial tissue and mesenchymal tissue. Renal pelvis and renal calices sarcomatoid carcinoma is very rare in the clinical practice. The incidence of this disease is unclear. According to the literature search, less than 30 cases of sarcomatoid carcinoma are reported until now. This study describes the clinical features of this case and reviews the pathology, immunohistochemistry, treatment and prognosis in accordance with the available literature.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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