Brain Syndemics: Cognitive Deficit, Pathways of Interaction, and the Biology of Inequality

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments: The Conclusion states that the brain syndemics orientation is potent to improve the health and health-related policy. This further provides an overview of how a small increase in family income has a significant impact on the brains of poor children and how to keep children out of the poverty line. Lastly, it concludes that the study can help to investigate the impact on the syndemic factors.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Not applicable.

Writing style

Q: Is it clear and understandable?

A: Good

Comments: There are few issue found in the manuscript which are as follows:

·       Under subheading Chronic Stress, 2^nd paragraph, 2^nd sentence, “As Blair and Raver (64:1) stress..” must be written as “As Blair and Raver states..”.

·       Under Interaction of Malnutrition and Toxins, 1^st sentence, “Observed Miller and Rayalam..” must be “Miller and Rayalam observed..”. And in 3^rd sentence, “Add Bharatraj and Yathapu..” must be “Bharatraj and Yathapu added..”.

·       In Conclusion, 1^st paragraph, 2^nd sentence, “investigation of the role social interventions can play in limiting harm..” must be rewritten as “investigation of the social role interventions can play limiting harm..”.

Further comments on the paper

Comments: This manuscript reviews the brain syndemics highlighting the relevant bodies of research on the biology of inequality and cognitive deficiencies. The paper further elaborates the pathways affected by factors such as poverty, chronic stress, malnutrition, air pollution, and other toxin exposures that co-relate syndemically to socio-economic inequality and brain development. Most importantly, the findings state that the deficiencies are not permanent and can be reversed once taken care of the socio-economic factors.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Thanks,
Science Repository Team