In Vitro Migration of Porcine Adipose-Derived Stem Cells in Platelet-Rich Plasma

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The study is well designed and executed. The Methods and Results are adequately described. The Discussion offers a thorough and detailed analysis of the findings of the present study taking all the relevant literature into account. It is well supported with briefly explained figures. The experiments aim to determine an optimal concentration of platelet-rich plasma that increased adipose-derived stem cell proliferation and migration while maintaining long-term cell viability. The Concluding statement that platelet-rich plasma at the appropriate concentration increases proliferation, migration, and velocity of cell spreading is consistent with the evidences presented in this article.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments:

This article studies the in vitro migration of porcine adipose-derived stem cells in platelet-rich media. The Introduction lays down the basics for taking up the present study clearly. The study throws light upon the necessity of further characterization of platelet-rich plasma (PRP) and its effects on adipose-derived stem cells (ASCs) to tease out the specific growth factors responsible for the increase in swine ASC migration before the beginning of extensive clinical trials.

Q: Would you recommend this manuscript for further publication?

A: Yes, suitable for publication.

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Science Repository Team