Lynch Syndrome and Breast Cancer: Case Reports and Literature Review

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The Discussion provides an apt analysis of the various important aspects of breast cancer screening along with the potential risks of Lynch syndrome (LS). It is important to distinguish with genetic screening testing if cancer in the cases of breast cancer, ovarian cancer, colon cancer and endometrial cancer is sporadic or hereditary. The Conclusion section summarizes from the review that it is important to recognize individuals who may have Lynch Syndrome and belong to a high-risk group. People with this syndrome should be advised on the benefits of prophylactic surgery for ovarian, endometrial, breast and colon cancer.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: This case report and literature review reports 3 different cases of women presenting with breast malignancy, later revealing Lynch syndrome (LS). It is important to diagnose LS as early as possible, because of the increased lifetime risk of developing cancer. Breast cancer associated with known LS constitutes a challenge for the medical community and women with LS are also at increased risk for several malignancies. The report aims to understand LS and get acquainted with LS presenting breast cancer.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Thanks,
Science Repository Team