Heyde’s Syndrome – A Forgotten Association

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Excellent

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The Discussion puts forth the rationale for taking up the study, effectively describes the relevant literature and enlists the implications of the findings from the present study in that context. It discusses from review of the literature that treatment options for Heyde’s syndrome range from medical treatment to an Aortic valve replacement (AVR) but must be tailored to the individual patients’ preferences and co-morbidities. However, despite surgical reticence, replacement of the stenosed aortic valve in Heyde’s Syndrome has been shown to be effective in stopping the recurrent bleeding episodes and resulting in haematologic recovery.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Not applicable

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: This report presents the case of an 80-year-old man admitted on 15 separate occasions over a period of two years with recurrent episodes of epistaxis on a background of recurrent gastrointestinal bleeds and aortic stenosis. Recurrent epistaxis is an interesting and rare additional complication of Heyde’s syndrome, with only one reported case in English literature. In patients with recurrent epistaxis that fail to respond to conventional conservative therapy, this case hopes to show the importance of the consideration of a more complex etiology thereby making the investigation of other underlying diagnoses also important.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team