Supratentorial Hemangioblastoma in a Filipino Male with Von-Hippel Lindau: A Case Report and Systematic Review

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The patient in this case report underwent open radical right nephrectomy with no adverse perioperative events. The case description is adequate. The Discussion explains the challenges in treating the patient in the present case clearly. It also offers useful suggestions with respect to the treatment regimen. It offers a thorough and detailed analysis of the findings of the present study taking all the relevant literature into account. The study is well supported with briefly explained figures. The case report finally concludes that a delay in recognition and diagnosis of von-Hippel Lindau (vHL) syndrome can lead to increased morbidity and mortality from serious complications such as advanced renal carcinoma.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This case report presents the case of a 58-year-old Filipino male with unremarkable family history who presented with progressive right homonymous hemianopia. The study holds significance as it is the first documented case of a supratentorial hemangioblastoma in a Filipino with von-Hippel Lindau (vHL) and one of the very few reported in the country. Diagnosis of this disease condition is challenging as it involves a high degree of suspicion and performance of several diagnostic tests which can be physically and financially taxing to the patient. This case highlights the importance of maintaining a high index of suspicion to prompt search for other associated disease features in any patient presenting with a typical vHL lesion.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team