Malignancy of Aneurysmal Bone Cyst in Osteosarcoma and Angiosarcoma: Series of 2 Cases and Literature Review

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them coherent?

A: Very good

Comments:

The case descriptions are adequate. The Discussion puts forth the rationale for taking up the study, effectively describes the relevant literature and enlists the implications of the findings from the present study in that context. It explains the challenges in treating the patient in the present case clearly. It also offers useful suggestions with respect to the treatment regimen. The reports are well supported by briefly explained figures. The Conclusion section is apt in confirming not only the malignant potential of these tumors, but also how this study broadens the spectrum towards epithelioid angiosarcoma.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legends and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This case report and review of the literature presents the case of two patients with an initial histologic diagnosis of aneurysmal bone cyst (ABC) who developed true malignancy. This study holds significance as epithelioid angiosarcoma from an ABC tumor malignancy has never been described before in literature. Also, very few cases in the literature support the existence of malignant ABC tumors in the absence of risk factors such as radiotherapy.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Thanks,
Science Repository Team